中药治疗精神药物便秘副作用68例临床观察

Clinical Observation on Traditional Chinese Medicine in the Treatment of 68 Cases of Constipation Caused by Psychoactive Drug

目的:观察中药治疗精神药物便秘副作用的疗效。方法:将134例因使用精神药物致便秘的患者随机分为2组观察治疗,治疗组68例,口服中药(以麻子仁丸为主),对照组66例,使用果导片治疗。用记分法评价疗效。结果:治疗组痊愈46例,显效16例,好转5例,无效1例,总有效率98.53%,1月内复发9例;对照组痊愈36例,显效18例,好转7例,无效5例,总有效率92.42%,1月内复发24例;2组总有效率比较,差异无显著性意义(x2=1.67,P>0.05),2组复发率比较,差异有显著性意义(x2=8.45,P<0.01),结论:中药对精神药物所致便秘疗效较好。

Objective： To observe the effect of traditional Chinese medicine in treating constipation caused by psychoactive drug. Method： 134 cases with constipation caused by psychoactive drug were randomly divided into two groups, 68 cases in treatment group were orally taken traditional Chinese medicine （the main composition was cannabis seed bolus）, while 66 cases in control group were treated by phenolphthalein tablet. The effect was evaluated by score method. Results： In treatment group, 46 cases were fully recover, 16 cases had obvious effect, 5 cases had effect, 1 case had no effect, the total effective rate was 98.53%, and the number of recurrence after one month was 9; while in control group, 36 cases were fully recover, 18 cases had obvious effect, 7 cases had effect, 5 cases had no effect, the total effective rate was 92.42%, and the number of recurrence after one month was 24. The total effective rates of two groups had no obvious difference （x^2 = 1.67, P〉0.05）, while the recurrence rates had significant differences （x^2 =8.45, P〈0.01）. Conclusion： Traditional Chinese medicine has better effect in the treatment of constipation caused by psychoactive drug.