铜绿假单胞菌下呼吸道感染126例耐药性分析

Resistant analysis of 126 senile cases of lower respiratory tract infection by Pseudomonas aeruginosa

目的探讨铜绿假单胞菌下呼吸道感染和对抗菌药物的耐药状况。方法使用纸片扩散法（K—B法）进行药敏试验。结果铜绿假单胞菌耐药率〈20％的抗菌药物有亚胺培南、头孢吡肟、头孢哌酮／舒巴坦和氨曲南；头孢他啶、哌拉西林／他唑巴坦、喹诺酮类的耐药率在20％～40％之间；哌拉西林、头孢噻肟、阿米卡星、庆大霉素、奈替米星、妥布霉素的耐药率在50％～70％之间；耐药率最高的是复方新诺明，达100％。结论临床上由铜绿假单胞菌引起的呼吸道感染日益增加，耐药率不断增高，应加强对铜绿假单胞菌的耐药性监测。

Objective To study the respiratory tract infection caused by Pseudomonas aeruginosa and the resistance situation. Methods The biochemical and serologic tests were used to detect the susceptibility of bacterium to antimicrobials, Results The resistance rate of imipenem,cefoperazone/sulbactam,aztreomam and cefepime was below 20% ;the rate of ceftazidime, piperacillin/tazobactant and quinolones was between 20% - 40% ; the rate of piperaeillin, cefotaxime, amikacin, gentamicin, netilmicin,tob - ramycin was between 50% - 70% ; the resistance rate of trimethoprim - sulfamethoxazde was 100%. Conclusion The respiratory infections disease which aroused by Pseudomonas aeruginosa in clinical is increased day and day, and the resistance rate is raised. It is important to strengthen the test of resistance of Pseudomonas aeruginosa.