气质联用法测定保健品中二乙烯苯溶剂残留

Determination of divinylbenzene solvent residual in health products by gas chromatography-mass spectrometry

目的：建立保健品中二乙烯苯溶剂残留的检测方法。方法：采用挥发油提取法提取样品中的二乙烯苯,以分离样品中的油脂,气质联用选择离子方式（GC-MS-SIM）检测样品提取物中的二乙烯苯。结果：在0.2～10μg/ml范围内线性良好,相关系数0.9992;按取样5 g计算,检测限为20μg/kg;按50、100、150μg/kg的量作加标回收实验,回收率为82%～93%;重复测定5次,相对标准偏差为5.4%～8.7%。结论：方法能有效分离样品中油脂,去除其它挥发性成分的干扰,检测限低于50μg/kg的限量值,能满足日常检测的要求。

Objective： Gas chromatography-mass spectrometry（GC-MS） was reported in this paper for the determination of divinylbenzene solvent residual in health products.Methods：Divinylbenzene was separeted from sample matrix such as fat with naphtha distilled method and detected by GCMS-SIM.Results：Good linearity was found between 0.2～10 μg/ml with r2=0.9992.LOD was 20 μg/kg and rescovery 82%～93%.RSD was 5.4%～8.7%（n=5）.Conclusion：The interfering of fat and some other volatile compounds can be wiped off effectively.