孕妇梅毒血清学筛查3种方法比较

Compare of the three detection methods of syphilis serology among pregnant women

目的:探讨孕妇梅毒筛查方法。方法:用TP-ELISA与TRUST同时对12600例孕妇做梅毒筛查,收集阳性总计87例血清-70℃保存,然后再统一用3种方法复检。结果:12600例孕妇TP-ELISA法阳性84例,占0.67%,TRUST阳性41例,占0.32%,TP-ELISA法与TPPA的符合率为98.8%。结论:为降低梅毒对妇婴的危害,应推广特异性血清学试验与非特异性血清学试验联合做为筛查,阳性的加做TRUST滴度。

Objective： To compare the screening test methods of syphilis infection among pregnant women.Methods：Use TP-ELISA and TRUST to detect syphilis infection among 12600 pregnant women,and collect 87 positive blood serum to storage at-70℃ preparing for reinspection by three test methods.Results：Among 12600 pregnant women,84 were positive by TP-ELISA（positive rate 0.67%）,41 were positive by TRUST（positive rate 0.32%）.The accordance rate of the two methods was 98.8%.Conclusion：To reduce the harm of syphilis to mothers and infants,we should generalize the combined method of the specific and nonspecific serology tests,and do TRUST titer test when positive.