脑血栓形成患者血清HDL-C及其亚类和ApoB含量测定及其临床意义

Clinical Significance of Determination of Serum HDL-C and Its Subclasses,and ApoB in Patients with Cerebral Thrombosis

40例脑血栓形成患者和40例健康人血清 HDL-C 及其亚类(HDL_2-C、HDL_3-C)和ApoB 的检测结果表明:病人组 HDL-C 和 HDL_2-C 低于对照组,HDL_2-C 降低尤为明显;而血清 ApoB含量则明显高于对照组(P<0.01).作者认为:HDL_2-C 显著下降和 ApoB 显著增高是脑血栓形成的危险因素.

Serum levels of H DL-C,HDL_2-C,HDL_3-C and ApoB were measure in 40 subjects with cerebral thrombosis and in 40 normal subjects as a control group.Lower levels of serum HDL-C and HDL_2-C were noted in the patients with cerebral thrombosis than those in the control,especially the HDL_2-C level being much lower,while the level of ApoB was much higher than that in the control(P< 0.01).No significant change was found in the serum levels of HDL_3-C and total cholesterol(P> 0.05).It was suggeted that lowered HDL_2-C and increased ApoB levels in the serum might be risk fac- tors in cerebral thrombosis.