造血干细胞移植在小儿神经母细胞瘤治疗中的应用进展
摘要
神经母细胞瘤(NB)是儿童外周神经系统最常见的恶性肿瘤,约占儿童肿瘤的10%.儿童肿瘤死产人数的50%,有关NB的治疗研究进展颇为迅速,已从单纯的外科治疗逐渐发展为以放疗、化疗及内分泌、生物、免疫治疗等为基础的综合治疗。近30年来,随着造血干细胞移植(HSCT)技术的成熟,这一技术被尝试推广应用于治疗一系列实体瘤中,其中对于晚期、高危及复发NB,国内外研究者进行了大量的临床实践,在有所发现的同时也出现了一些问题和分歧,下面就此做一综述。
出处
《中华小儿外科杂志》
CSCD
北大核心
2008年第6期377-380,共4页
Chinese Journal of Pediatric Surgery
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共引文献27
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