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造血干细胞移植在小儿神经母细胞瘤治疗中的应用进展

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摘要 神经母细胞瘤(NB)是儿童外周神经系统最常见的恶性肿瘤,约占儿童肿瘤的10%.儿童肿瘤死产人数的50%,有关NB的治疗研究进展颇为迅速,已从单纯的外科治疗逐渐发展为以放疗、化疗及内分泌、生物、免疫治疗等为基础的综合治疗。近30年来,随着造血干细胞移植(HSCT)技术的成熟,这一技术被尝试推广应用于治疗一系列实体瘤中,其中对于晚期、高危及复发NB,国内外研究者进行了大量的临床实践,在有所发现的同时也出现了一些问题和分歧,下面就此做一综述。
出处 《中华小儿外科杂志》 CSCD 北大核心 2008年第6期377-380,共4页 Chinese Journal of Pediatric Surgery
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参考文献31

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