天津市部分医务人员鼻腔带菌及其耐药情况的调查

Bacteria Nasal Carriage and Antibiotic Susceptibility in Medical Staff in Tianjin

目的了解天津市医务人员鼻腔带菌及其耐药情况。方法于2007年4月至10月,随机选择天津市11家三级医院和9家二级医院的299名医护人员为调查对象,以灭菌棉拭子涂抹双侧鼻腔采样,对分离到的致病菌或条件致病菌做药敏试验。结果在299份鼻腔拭子样本中共有125份带菌,检出率为41.80%,分离到致病菌或条件致病菌菌株136株,以肺炎克雷伯菌、金黄色葡萄球菌和产气肠杆菌为主要菌种,其中对3种及3种以上抗生素耐药的有35株,占25.73%,检出耐甲氧西林葡萄球菌10株。结论本调查提示医务人员鼻腔带有致病菌与条件致病菌,部分细菌耐药较严重,应引起重视。

Objective To investigate and analyze nasal carriage of bacteria in medical staff and antibiotic susceptibility. Methods All study participants underwent swabbing of the anterior 1.5 cm of the nasal vestibule of both nares with a sterile swab,and did drug sensitivity test Apr.-Oct.,2007. Results In 41.08% of all samples （125/299）,136 pathogenetic bacteria were isolated. Klebsiella pneumoniae,Staphylococcus aureus and Enterobacter aerogenes were the prominent bacteria,of which showed the resistance for more than three kinds of antibiotics were 35,accounting for 25.73% of all isolates,10 strains of Methicillin-resistant Staphylococcus （MRS） were detected. Conclusion The nasal carriage of bacteria and antibiotics resistance in medical staff in Tianjin should be paid attention to,for it may an important factor in the control of infection in hospitals.