1-硝基-3-三氯乙烯基苯的制备

Preparation of 1-Nitro-3-trichlorovinybenzene

1-硝基-3-三氯乙烯基苯（1）是广谱兽用驱虫药氯舒隆（clorsulon）的重要中间体^[1,2]。文献^[3,4]用三苯膦和三氯甲烷反应生成二氯亚甲基三苯膦（dichlormethylene triphenyl phosphine，Ph，P=CCl2），不经分离，直接与乙酰基苯反应，最后硝化得1，总收率为32％。文献^[5]以苯为原料，与乙酸钠、AlCl3反应得乙酰基苯，

1-Nitro-3-trichlorovinybenzene, a key intermediate of clorsulon was prepared from 3-nitrobenzaldehyde with chloroform by condensation, chlorination and elimination with an overall yield of 85 %.