期刊文献+

多西他赛联合调强放疗治疗非小细胞肺癌 被引量:1

下载PDF
导出
摘要 约2/3的非小细胞肺癌(NSCLC)患者确诊时己失去手术机会,常需采用放化疗为主的综合治疗。调强放射治疗(Intensitv modulated radiation therapy,IMRT)可明显改善靶区剂量的分布,同时最大程度降低正常组织受照射剂量,从而改善局部控制率:多西他赛(Docetaxel)是目前治疗NSCLC最有效的单药之一。笔者自2006—04~2007—05应用Docetaxel联合IMRT同期治疗Ⅲ~Ⅳ期NSCLC20例。旨在探讨每周方案Docetaxel单药联合1MRT同期治疗晚期NSCLC的疗效及临床耐受情况。
出处 《实用医药杂志》 2008年第8期925-926,共2页 Practical Journal of Medicine & Pharmacy
  • 相关文献

参考文献5

  • 1吴开良,蒋国梁,廖源,钱浩,王丽娟,赵森.非小细胞肺癌三维适形放射治疗临床Ⅰ和Ⅱ期剂量递增试验结果分析[J].中华放射肿瘤学杂志,2003,12(1):10-13. 被引量:113
  • 2Grills IS, Yan D, Martinez AA, et al. Potential for reduced toxicity and dose escalation in the treatment of inoperable non-small-cell lung cancer:, a comparison of intensity-modulated radiation therapy (IMRT), 3D conformal radiation, and elective nodal inadiation.Int J Radlat Oncol Biol Phys,2003,57(3):875.
  • 3Liu HH, Wang X, Dong L, et al. Feasibility of sparing lung and other thoracic structures with intensity-modulated radiotherapy for non-small-cell lung cancer.Int J Radiat Oncol Biol Phys, 2004,58(4):1268.
  • 4Hainsworth JD, Burris HA 3rd, Greco FA. Weekly docetaxel as a single agent and in combination with gemcitabine in elderly and poor performance status patients with advanced non-small- cell lung cancer.Semln Oncol, 2001,28(9):21.
  • 5Hainsworth JD, Vokes EE. Docetaxel (Taxotere) in combination with radiation therapy and the potential of weekly administration in elderly and/or poor performance status patients with advanced non-small cell lung cancer. Semin Oncol, 2001,28(2):22.

二级参考文献1

共引文献112

同被引文献13

  • 1刘秀芳,王炳胜,熊正文,李宏伟.微血管密度及增殖细胞核抗原表达与宫颈癌放射敏感性的关系初探[J].中国肿瘤临床与康复,2005,12(2):100-102. 被引量:5
  • 2郑伟,吴丽娜,吴荣.多西他赛联合放疗治疗Ⅲ期非小细胞肺癌的临床观察[J].中华肿瘤防治杂志,2006,13(18):1424-1425. 被引量:17
  • 3Vokes EE, Herndon JN, Kelley M J, et al. Induction chemotherapy followed by ehemoradiotherapy compared with chemoradiotherapy a- lone for regionally advanced unresectable stage BI non small - cell lung cancer: cancer and leukemia group B [ J ]. J Clin Onco1,2007, 25 : 1698 - 1704.
  • 4Hainsworth JD, Burris HA 3rd, Greco FA. Weekly docetaxel as a single agent and in combination with gemcitabine in eldedy and poor performance status patients with advanced non - small - cell lung cancer [ J ]. Semin Oncol, 2001,28 ( 9 ) : 21.
  • 5Dancey J, Shepherd FA, Gralla R J, et al. Quality of life assessment of second - line docetaxel versus best supportive care in patients with non - small - cell lung cancer previously treated with platinum -based chemotherapy;results of a prospective randomized phase Ill trial [J]. Lun: Cancer.2004.43:183.
  • 6Folk - man J. What is the evidence that tumors are angiogenesis denpendent [ J]. J Natl Cancer Inst, 1990,82:4 - 6.
  • 7Fischer S, Renz D, Schaper W, et al. Invitro effect of dexametha- sone on hypoxia induced hyperpermeabilitu and expresion of vas- cular endothelial growth factor [ J]. Eur J Phannacol,2001,411 (3) :231.
  • 8H ennequ in C. Association of taxanes and radiotherapy : preelini- cal and clinical studies [ J ]. Cancer Radiother,2004,8 (Suppl 1 ) : $95 - S105.
  • 9Qinghua Zhou, Lunxu Liu, Lu Li, et al. A randomized clinical trial of preoperative neoadjuvant chemotherapy followed by surgery in the treatment of stage ]II non - small cell lung cancer [ J ]. Lung Cancer,2003,41 ( $2 ) : $45 - $46.
  • 10孙燕,李维廉,管忠震,李丽庆,张湘茹,吴海鹰,朱思伟,梁艳,刘鹏,翟宇,张和平,魏开福.泰索帝治疗晚期乳腺癌和肺癌[J].中国新药杂志,1998,7(3):105-107. 被引量:65

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部