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疫苗佐剂的分类和作用方式 被引量:3

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摘要 本世纪初疫苗中已使用佐剂来增强疫苗效力,但迄今人用甚至兽用疫苗的佐剂大多数仍为铝盐。近年来许多新疫苗正在开发中,并期望通过增加疫苗组分和减少剂数来简化免疫程序,这就需要更有效的新佐剂。本文讨论佐剂的发展和作用方式,并尝试根据作用方式进行佐剂分类,以期有助于佐剂的选择。
出处 《国外医学(预防.诊断.治疗用生物制品分册)》 1997年第6期253-258,共6页 Foreign Medical Sciences(Section of Bilogics for Prophylaxis,Diagnosis and Therapy)
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  • 1Hong-TaoLi,Jia-BinYan,JingLi,Ming-HaiZhou,Xiao-DongZhu,Yu-XiaZhang,PoTien.Enhancement of humoral immune responses to HBsAg by heat shock protein gp96 and its N-terminal fragment in mice[J].World Journal of Gastroenterology,2005,11(19):2858-2863. 被引量:6
  • 2Marciani DJ. Vaccine adjuvants: role and mechanisms of action in vaccine immunogenicity[J]. Drug Discov Today, 2003, 8(20):934-943.
  • 3Corsi K, Chellat F, Yahia L, et al. Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan-DNA nanoparticles [J]. Biomaterials, 2003, 24(7): 1255-1264.
  • 4Romoren K, Thu B J, Evensen O, et al. Immersion delivery of plasmid DNA. Ⅱ . A study of the potentials of a chitosan based delivery system in rainbow trout ( Oncorhynchus mykiss) fry [ J ]. J Control Release,2002, 85(1-3) :215-225.
  • 5Synowiecki J, A1-Khateeb NA. Production, properties, and some new applications of chitin and its derivatives[J]. Crit Rev Food Sci Nutr,2003, 43(2) :145-171.
  • 6Risbud M, Bhonde M, Bhonde R. Chitosan-polyvinyl pyrrolidone hydrogel does not activate macrophages potentials for tranplantation applications[J]. Cell Transplant, 2001, 10(2) :195-202.
  • 7Vord PJ, Matthew HW, Silva SP, et al. Evaluation of the biocompatibility of a chitosan scaffold in mice[J]. J Biomed Mater Res, 2002, 59(3) :585-590.
  • 8Shibata Y, Foster LA, Bradfield JF, et al. Oral administration of chitin down-regulates serum IgE levels and lung eosinophilia in the allergic mouse[J]. J Immunol, 2000,164(3): 1314-1321.
  • 9Shibata Y, Honda I, Justice JP, et al. Thl adjuvant N-acetyl-D-glucosamine polymer up-regulates Th1 immunity but down-regulates Th2immunity against a Mycobacterial protein(MPB-59) in interleukin-10-knockout and wild-type mice[J]. Infection and Immunity, 2001, 69(10) :6123-6130.
  • 10Shibata Y, Foster LA, Metzger WJ, et al. Alveolar macrophage priming by intravenous administration of chitin particles, polymers of Nacetyl-D-glucosamine, in mice [ J ]. Infection and Immunity, 1997, 65(5): 1734-1741.

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