摘要
本文对用药两周后绿脓杆菌、大肠杆菌及金黄色葡萄球菌感染的创面进行了组织学和组织化学检查表明:①用药两周后,经绿脓杆菌感染的创面,伤缘的表皮厚度增加,新生上皮增多,肉芽组织生长良好,同对照组相比,差异有显著性(P<0.01);伤缘表皮和新生上皮中的糖原和核糖核酸含量同对照组相比差异无显著性(P>0.05),说明酸性中草药灭菌液Ⅱ号(pH4)能促进上皮增生和肉芽组织生长;②中草药灭菌Ⅱ号对金黄色葡萄球菌和大肠杆菌的作用较差,这可能与这两种细菌的适应环境能力有关。
60 rabbits were used to burn on the back with a hot iron,the burned area was 3 cm×3 cm, They are divided into 6 groups three of them were used as experimental groups,which were inoculated respectively by Psevdomonas aeruginosa,B.coli,and Staphylococcus aureus.The other three groups were used as control groups.After 5 days' inoculation,the experimental groups were treated with Chi- nese medical herbes-Bactericial Ⅱ,and-the control groups were left Without any treatment.The re- sults showed:(1)after 2 weeks' therapy,the epithelium of the edge of the burned wound became thicker and the new-born epithelium under the burned surface increased more than that of the control group.The grnulation tissue also grew better than that of the control group.(2)the quantities of glycogen and RNA in the epithelium of the wound edge and in the new-born epithelium were not dif- ferent from that of the control groups.(3)the therapeutic effect of Bactericide Ⅱ(acidic)on pseu- domonas aeruginosa was stronger than that of drug on B.Coli and Staphylococcus aureus.It might be concluded that Bactericide Ⅱ(expcept its inhibition action on bacteria)could promote the growth rate of the epithelium on the edge of the wound and the granuIation tissue under the burned surface.
