摘要
本文报告了12例 TIA 病人的临床表现和治疗措施。为降低病死率,对 TIA 急性期抗菌素、糖皮质激素和血液制品的合理应用提出了讨论。
Clinical features and therapeutic methods were studied in 12 cases(aged 19 to 55 years)with tapa- zol-induced agranulcytosis(TIA).The lowest values of leucocyte and granulocyte were 0.4×10~9/L and zero respectively in the group of the patients.The percentages of the patients complicated with up- per respiratory tract infection,mouth ulcer and septicaemis were 66.7%,50.0% and 33.3%,respec- tively.Of all the cases,l0 recovered and 2 died affer general treatment.In order to decrease death rate,the following three therapeutic approaches should be considered in addition to stopping tapazol and using leucocyte-increasing medications:(1)Application of effective and sensitive new beta-lactam an- tibiotics.(2)Application of glucocorticoid to the patients complicated with septicaemia.(3)Infusion of leucocyte suspension in acute phase.
