大黄在治疗重症胰腺炎中的临床疗效观察

The effect of rhubarb in treatment of severe pancreatitis

目的探讨大黄对重症胰腺炎的治疗价值。方法40例重症胰腺炎患者随机分为大黄组(治疗组)和对照组。除常规治疗外,治疗组服用大黄25g/d,共5d。对照组不服用大黄。观察两组腹痛、腹胀症状,血淀粉酶,住院时间、费用的变化。结果治疗组腹痛、腹胀缓解快,血淀粉酶下降早,住院时间和费用少,与对照组比较差异有统计学意义(P<0.05)。结论大黄能有效缓解重症胰腺炎的临床症状,缩短病程。

Objective To investigate the clinical efficacy of rhubarb in treatment of severe pancreatitis.Methods A total of 40 patients with severe pancreatitis were selected and divided randomly into two groups： rhubarb group and control group.In addition to normal regulations treatment,in rhubard group the patients received rhubarb（25 g/d） for 5 days,while in control group the patients were not be taken rhubarb.The changes of symptom of abdominal fullness,abdominal pain,the levels of amylase,staying in the hospital time and expenses were investigated between the two groups.Results In rhubarb group,rhubarb greatly improved the symptom of abdominal fullness and abdominal pain,the levels of anaylase were decreased early.Staying in the hospital time and expenses were significantly decreased.Conclusion Rhubarb and is an effective therapy for symptom of severe acute pancreatitis.