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坎地沙坦酯及氨氯地平对中重度高血压患者左心室肥厚的影响 被引量:1

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摘要 目的观察坎地沙坦酯、氨氯地平对中、重度原发性高血压患者左心室肥厚(LVH)的影响。方法80例原发性高血压合并左心室肥厚患者口服坎地沙坦酯8mg/d,苯磺酸氨氯地平5~10mg/d。服药前和服药后24、36周,应用超声心动图测量左心室的结构变化:结果80例患者顺利完成研究,超声心动图显示坎地沙坦酯、苯磺酸氨氯地平治疗24周后,左心室重量(LVM)、左心室重量指数(LVMI)降低,舒张末期室间隔厚度(JVsT)和左心室后壁厚度(PwT)变薄;继续治疗至36周,上述指标降低更明显。结论坎地沙坦酯、苯磺酸氨氯地平对中、重度高血压患者在有效降低血压的同时,可逆转心室肥厚。
作者 曾显峰
出处 《临床医学》 CAS 2008年第8期63-64,共2页 Clinical Medicine
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