子宫动脉栓塞术治疗子宫肌瘤的临床研究

Clinical efficacy of uterine artery embolization in the treatment of uterine myoma

目的评价子宫动脉栓塞术(UAE)治疗子宫肌瘤的临床效果。方法对49例经临床、超声或MRI诊断为子宫肌瘤的患者行UAE,采用Seldinger技术经股动脉穿刺,将导管选择性插入双侧子宫动脉,经导管注入聚乙稀醇颗粒(PVA)、海藻酸钠微球(KMG)或明胶海绵微粒栓塞,阻断肌瘤供血动脉。术后定期观察月经量、一般症状、子宫与病灶体积变化。结果术后所有患者临床症状均有明显改善或消失,月经恢复正常,子宫肌瘤均有不同程度的缩小,无严重并发症发生。结论动脉栓塞治疗子宫肌瘤是一种微创性的治疗手段,可使肌瘤进行性缩小,临床症状改善,是子宫肌瘤临床治疗的又一种选择。

Objective To assess the clinical efficacy of uterine artery embolization （UAE） in the treatment of uterine myoma.Meth- otis Forty-nine patients with uterine myoma which was definitely diagnosed via clinical follow-up,ultrasound or MR imaging underwent UAE.All the interventional procedures were performed by using Sildinger＇s technique,i＋e.SF Cobra cathetes were super-selectively inserted into bilateral uterine arteries and then the embolic agents which comprised PVA,KMG or gelatin sponge particles mixed with antibiotic drugs were perfused to embolize tumoral supply arteries.After the operations,All the patients whose menstruous state,clinical symptoms and changes of uterine and tumoral volume were periodically observed and comparatively studied with preoperative findings.Results The study demonstrated that all patients whose clinical symptoms were obviously relieved or even disappeared,the menstruation most retured to normality,uterine and tumoral volume were significantly reduced after operation,simultaneously there were no severe complications related to UAE porcedure. Conclusion Because UAE decidedly resulted in tumor volume reduction and clinical symptom improvement,thus,it is a very effective means for treating uterine myoma.