^(99m)Tc-MIBI肺/心比值作为冠心病患者左室功能参数的研究

The L/H Ratio of 99m Tc-MIBI as a Parameter of Left Ventricular Function in Coronary Artery Disease

测定了对照组、冠心病组中９９ｍＴｃ－ＭＩＢＩ肺／心比值（Ｌ／Ｈ）。结果表明：静息或负荷心肌显像时，冠心病组Ｌ／Ｈ均明显高于对照组。冠心病组中，Ｌ／Ｈ与左室射血分数（ＬＶＥＦ）呈显著负相关；Ｌ／Ｈ增高者与正常者相比，心肌灌注节段和室壁运动评分均明显高（Ｐ＜０．０１）。逐步回归分析证实了ＬＶＥＦ是影响静息Ｌ／Ｈ的独立因素。提示：心肌显像的同时测定Ｌ／Ｈ，能提供冠心病病变的程度、范围及心功能障碍的有用信息，是评价左室收缩功能简便、实用的方法。

e measured in two groups. The result showed that the L/H ratio in patients with coronary artery disease (CAD) were markedly higher than that in the control both at rest and during stress. A significant inverse correlation between L/H and left ventricular ejection fraction (LVEF) was found in patients with CAD. The patients with an elevated L/H had a greater number of segments with abnormal wall motion and bypoperfusion than those with normal L/H. Stepwise regression analysis demonstrated that LVEF was an independent impact factor of L/H at rest. In conclusion, L/H may provide useful information regarding the extent and the severity of CAD.