冠心病左心室舒张功能对心肌复极离散度的影响

Effect of left ventricular diastolic function on cardiac muscle repolarization dispersion in patients with coronary heart disease

为观察左心室舒张功能与心肌复极离散度的关系,采用脉冲多普勒测定左心室收缩功能正常的56例冠心病及20例健康人的左心室舒张功能,同时描记并测量两组病人心电图有关指数。结果显示:(1)冠心病组病人E、A、A/E、Q-T_d、Q-T_(cd)、J-T_d、J-T_(cd)改变较对照组明显(P<0.01)。(2)冠心病组E、1/2DecT与Q-T_d、J-T_d、J-T_(cd)呈显著负相关(P<0.01)。(3)健康对照组病人E、A、A/E、1/2DecT与Q-T_d、Q-T_(cd)、J-T_(cd)的相关性分析,差异无显著意义(P>0.05)。提示冠心病有左心室舒张功能异常病人的心肌复极离散度增加,冠心病人左心室舒张功能异常与心肌复极之间有良好的相关性。

To observe relations of left ventricular diastolic function (LVDF) to cardiac muscle repolarization dispersion. LVDF of 56 patients of normal left ventricular systolic function with coronary heart disease (CHD) and 20 normal subjects were measured using plused doppler echocardiography, recording and mea-suring related values of electrocardiogram. Results showed:(1) Changes of E 1/2DecT Q-T dispersion (Q-Td) J-T dispersion (J-Td) J-Tc dispersion (J-Tcd) were significant in CHD group than in normal subject group ( P<0. 01 ).(2) There were more positive relations of E 1/2 DecT to Q-Td, J-Td J-Tcd in CHD group, respectively ( P<0. 01 ). (3) There were no significance correlation in E A A/E,l/2 DecT to Q-Td,Q-Tcd,J-Td, J-Tcd in normal subject group, respectively ( P>0. 05 ). These indicated that abnormal LVDF might be accompanied by the increase of CMRD in CHD. Well correlation of abnormal LVDF with CMRD was found in CHD.