摘要
建立升黄克痛软膏的质量控制方法。采用薄层色谱法对方中主要药材大黄、升麻分别进行定性鉴别,采用高效液相色谱法测定大黄素、大黄酚含量。定性鉴别方法重现性好、专属性强,含量测定方法的平均回收率为99.92%和97.12%,RSD为1.75%和0.66%。质量控制方法简单、易行、精密度高、重现性好,能够有效地控制升黄克痛软膏的质量。
To establish a method for the quality control of Shenghuangketong Ointment, the qualitative analysis of Radix. et Rhizoma Rhei and Rhizoma Clmicifugue in Shenghuangketong Ointment were identified by TCL. The content of Emodin and Chrysophanol was determined by HPLC. The qualitative identification was specific and reproducible. The average recovery rate of quantitative analysis was 99.92% and 97.12% skeciall. Relative standard deviation was 1.75% and 0.66%. The precision and reproducibility of the method are good. The method can be used for the quality control of Shenghuangketong Ointment.
出处
《科学技术与工程》
2008年第17期4969-4972,共4页
Science Technology and Engineering
