摘要
分析口腔颌面部血管瘤和血管畸形的肥大细胞数量与雌激素受体(ER)水平及其在血管瘤增殖中的作用。方法:采用甲苯胺蓝染色法及免疫组化法对34例血管成和14例血管畸形病理标本进行分析。结果:血管瘤增殖期与退化期肥大细胞数量之间的差别有高度统计学意义(P<0.01);ER(-)与ER(++)时的肥大细胞数量之间的差别有高度统计学意义(P<0.01);血管瘤增殖期与退化期ER阳性率的差别无统计学意义(P>0.20)。结论:肥大细胞计数有助于血管瘤与血管畸形的鉴别诊断;ER(++)时有较多的肥大细胞参与血管瘤的生长。血管瘤增殖期比退化期的ER可能更具有活性。
Objective: To study the mast cell count, estrogen recoptor level and their role in the proiferation of hemangioma. Methods: The touidine blue stain and immunohistochemical technique were carried out.Results:The mast cell count in proliferative stage was higher than that in involuting stage (P< 0. 01). The mast cell count in ER " - " patients was lower than that in ER " + + " ones(P< 0. 01). The positive rate of ER had no significant different between proliferative and involuting stage hemangiomas (P> 0. 20).Conclusion: Mast cell count can help the differential diagnosis of hemangioma and vascular malformation.There are more mast cells taking part in the growth of hemangioma in ER " + + " patients. The activity of ER in proliferation stage may be higher than that in involuting stage.
出处
《北京医科大学学报》
CSCD
1997年第6期530-532,共3页
Journal of Peking University(Health Sciences)
关键词
口腔颌面部肿瘤
血管瘤
血管畸形
肥大细胞
Hemangioma Vascular/abnorm Mast cells Receptors
estrogen Facial neoplasms