摘要
目的:观察皮内注射与皮下注射磷酸组胺对皮肤毛细血管通透性实验结果的影响。方法:建立组胺所致毛细血管通透性增加模型,尾静脉注射伊文思蓝,测定伊文思蓝的渗出。结果:皮内注射与皮下注射磷酸组胺均可造成实验用模型。结论:在小鼠皮肤毛细血管通透性实验中可采用皮下注射组胺的方法。
Objective: To study the effect of intradermal and subcutaneous histamine phosphate injecting on capillary permeability. Methods: Mouse model of capillary permeability increased was established by injecting histamine. The exudation of Evans blue was determined by injecting Evans blue in the vena caudalis. Results: Mouse model of capillary permeability increased was established by intradermal and subcutaneous histamine phosphate injecting. Conclusions : The method of histamine phosphate subcutaneous injecting was convenient. It can be applied in the capillary permeability experiment.
出处
《云南中医学院学报》
2008年第4期35-37,共3页
Journal of Yunnan University of Traditional Chinese Medicine
基金
云南中医学院教改课题"中药药理学探索性实验的组织与实施"
云南中医学院中药药理学重点学科建设项目
关键词
毛细血管通透性
皮内注射
皮下注射
磷酸组胺
Capillary Permeability
Intradermal Injection
Subcutaneous Injection
Histamine Phosphate