Effects of Needles with Different Diameters on the Gastrointestinal Emptying in Mice

目的:观察不同粗细毫针刺激对小鼠胃肠功能的影响。方法:将18只昆明种小鼠随机分为0.25 mm 细针组、0.35 mm 粗针组和对照组,每组6只,每天于固定时间分别刺激"足三里"穴,连续5天。通过检测小鼠肠内容物碳末推进距离,观察不同粗细毫针刺激对小鼠胃肠排空功能的影响。结果:三组碳末推进率比较,针刺组明显大于对照组(P<0.05)。粗针组大于细针组,但没有统计学意义(P>0.05)。结论:针刺可以提高小鼠胃蠕动功能,不同粗细针针刺对小鼠胃肠功能影响没有明显差异。

Objective： To observe the effects of needles with different diameters on the gastrointestinal function in mice. Methods： Eighteen Kunming mice were randomly divided into group of 0.25 mm needle, group of 0.35 mm needle, and control group. The acupoint of Zusanli （ST 36） was needled once a day for 5 days. The effects of needles with different diameters were observed by measuring the distance of the carbon moved in the intestine. Results： The distance of the carbon moved in the intestine was longer in the acupuncture group than in the control group （P〈0.05）, and it was longer in the group of 0.35 mm needle than in the group of 0.30 mm needle, there was no significant difference （P〉0.05）. Conclusion： Acupuncture treatment can enhance the peristalsis function of stomach and intestine in mice. The diameter of needle has no effect on the gastrointestinal function.