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子宫内膜异位症病灶的血管新生治疗进展 被引量:7

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摘要 子宫内膜异位症(EMs)是育龄妇女常见病和多发病,发病率呈上升趋势,其病灶有着类似恶性肿瘤种植生长和远处转移的生物学特点,药物治疗及手术治疗方案存在着不良反应大及复发率高等缺陷。近年研究表明,血管新生在EMs的种植、生长与播散中起到重要作用。现从动物模型子宫内膜异位样病灶和人体EMs病灶的血管新生角度阐述血管新生在EMs发病中扮演的重要角色,并总结体外、在体的血管抑制治疗的方法与进展,同时展望将来对EMs患者的治疗。为阐述EMs病灶的血管新生分子机制和今后EMs的治疗提供新思路。
出处 《国际妇产科学杂志》 CAS 2008年第4期271-274,共4页 Journal of International Obstetrics and Gynecology
基金 国家自然科学基金(编号:30672222) 广东省科技计划项目(编号:2006B50107001 2005B34201020 2007B080701011) 广东省自然科学基金项目(编号:0400377)
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