人工流产术后即时放置TCu380A、宫铜200的临床研究

A Clinical Study of TCu380A, UCDCu200 Inserted Immediately After Induced Abortion

目的评估人工流产术后即时放置TCu380A、宫铜200的临床效果、副作用、安全性、可接受性。方法采用前瞻性、随机对比研究方法，对100例健康、已生育的早孕妇女，由经过培训的医生以随机的方法在人工流产术后即时放置TCu380A50例（TCu380A组）、宫铜200IUD50例（宫铜200组），于放置后的1、3、6、12个月随访，以生命表法统计二种IUD的终止情况。结果使用12个月时，TCu380A、宫铜200的妊娠率均为0．0％妇女；脱落率分别为8．0、14．0％妇女，二组比较，差别无统计学意义（P〉0．05）；因症终止率分别为2．0、10．0％妇女，差别无显著性（P〉0．05）；续用率分别为88，0、72．0％妇女，TCu380A显著高于宫铜200（P〈0．05）。结论TCu380A、宫铜200于人工流产术后即时放置时避孕效果好、脱落率相对较低、续用率较高、安全、可接受性强、尤其是TCu380A，值得推广应用。

Objective To assess the clinical effects, side effects, safety and acceptability of TCu380A and UCDCu200 insertion immediately after induced abortion. Method A prospective, random clinical study was carried out. 100 healthy, parous and the first trimester pregnant women were randomly divided into TCu380A group （n = 50） , UCDCu200 group （n = 50） , IUD was inserted immediately after induced abortion by special training physician. Follow -up was arranged at 1, 3, 6, and 12 months after IUD insertion. The discontinuation rates were calculated by life table method. Result At the end of the first year, there was no pregnancy occurred in the two groups. The expulsion rate was 8.0, 14.0% cases, respectively, The expulsion rate was lower in TCu380A group than in UCDCu200 groups, but no statistical significant （P 〉 0. 05 ）. The other causes of removal rates were 2.0, 10.0% cases, respectively, no statistical significant （ P 〉 0. 05 ）. The continuation rate was 88.0, 72.0% cases, respectively. It was significant higher in TCu380A group than in UCDCu200 group（P 〈 0. 05 ）. Conclusion As excellent contraception efficacy, lower expulsion rates, higher continuation rates on TCu380A and UCDCu200, which were inserted immediately after induced abortion, they were recommend to wide spreading use.