摘要
目的对不同空腹血糖(FPG)状态下胰岛素抵抗(IR)的相关因素进行分析。方法将258例研究者分为四组:A组为FPG≤5.0mmol/L者65例;B组为5.0mmol/L<FPG<5.6 mmol/L者67例;C组为5.6mmol/L≤FPG<6.1mmol/L者64例;D组为6.1mmol/L≤FPG<7.0mmol/L者62例。测定FPG、空腹胰岛素(FIns)和血脂等生化指标,并进行统计学分析。结果(1)各组内甘油三酯(TG)、TG/高密度脂蛋白(HDL-C)值男性均高于女性(P<0.01,P<0.05);各组间TG、TG/HDL-C值有统计学意义(P<0.05)。(2)各组间FPG、胰岛素抵抗指数(Hom a-IR)有统计学意义(P<0.01)。(3)FPG、TG、TG/HDL-C与Hom a-IR正相关(P<0.01)。结论随着FPG增加,IR和TG代谢紊乱加重,IR与FPG、TG、TG/HDL-C比值呈正相关。
Objective To study insulin resistance (IR) in the different levels of fasting plasma glucose ( FPG), and to analyze their eorrelateion with IR. Methods According to the levels of FPG, 258 subjects were divided into Group A: ( FPG ≤5.0mmol/L, n = 65 ) ; Group B : (5.0mmol/L 〈 FPG 〈 5.6 mmol/L, n = 67) ; Group C: (5.6mmol/L ≤ FPG 〈 6.1 mmol/L, n = 64) ; Group D: (6. lmmol/L≤FPG 〈7.0 mmol/L, n =62). The levels of FPG, fasting insulin (Fins), fasting lipids in four groups were detected . The serum markers were studied. Results ( 1 ) TG and TG/HDL - C were higher in male groups than the female groups in four groups (P 〈0.01, P 〈0.05). TG and TG/HDL-C were significantly differed in four groups (P〈0.05). (2) In four groups, FPG and Homa - IR were significantly differed (P 〈0.01 ). (3) FPG, TG and TG/HDL - C was significantly correlated with Homa - IR (P 〈 0.01 ). Conclusion With FPG increasing, the severities of IR and dyslipidemia are increased. IR is correlated with FPG, TG and TG/ HDL - C.
出处
《宁夏医学杂志》
CAS
2008年第8期687-689,共3页
Ningxia Medical Journal
基金
宁夏银川市科技攻关项目(06-1-60)
关键词
空腹血糖
胰岛素抵抗
甘油三酯
Fasting plasma glucose
Insulin resistance
Triglyeride