摘要
目的观察舒芬太尼在骨科术后患者自控皮下镇痛(PCSA)中的应用效果。方法60例ASAⅠ～Ⅱ级的骨科手术患者,随机分为舒芬太尼组(S组)和吗啡组(M组),分别采用患者自控镇痛泵经皮持续输注舒芬太尼(2μg/h)和吗啡(0.4mg/h),观察记录两组患者的镇痛效果、生命体征变化及不良反应情况。结果S组的VAS评分在术后12、24及48h明显低于M组相应时刻的评分(P<0.05),S组镇痛期间恶心、呕吐、嗜睡等不良反应明显低于M组(P<0.05),两组镇痛期间生命体征均较平稳。结论舒芬太尼应用于患者自控皮下镇痛具有镇痛效果确切、可控性强及不良反应发生率低的优点,可安全用于骨科患者的术后镇痛。
Objective To observe the clinical effect of salfentanyl on patient-controlled subcutaneous analgesia（ PCSA）afier orthopaedic surgery. Methods Sxty ASA I～Ⅱ patients undergoing orthopaedic surgery were randomly divided into sulfentanyl group （group s, n = 30）and morphine group（group m, n = 30）. Group s received postoperative PCSA with sulfentanyl, contihu rate 2ug/h; Group m received postoperative PCSA with morphine,continue rate 0.4mg/h. The intensity of pain was evaluated using visual analogue scale（ VAS）. The mean arterial pressure （ MAP ）, heart rate （ HR ）, respiratory frequency （ R ） and pulse oxygen saturation （ SpO2 ） during analgesia were recorded. The side-effect during analgesia were investigated. Results The VAS pain scores were singificantly decreased in group s compared with those in the group m（ P 〈 0.05） .Less nausea,vomiting and other adverse reaction happened in group S than group m.The MAP,HR,R and SpO2 were stable in two groups.Conclusion Sulfentanyl could safely be used on patient-controlled subcutaneous analgesia after orthopaedic surgery.
出处
《四川医学》
CAS
2008年第8期1012-1014,共3页
Sichuan Medical Journal
关键词
舒芬太尼
患者自控镇痛
皮下镇痛
骨科
sulfentanyl
patient-controlled analgesia
subcutaneous analgesia
orthopaedic surgery
