摘要
葛根总黄酮５００，１０００ｍｇ／ｋｇ，连续ｐｏ７ｄ，能显著对抗反复性脑缺血大鼠脑组织含水量、Ｃａ２＋及丙二醛（ＭＤＡ）的含量升高，Ｃａ２＋－ＡＴＰａｓｅ及超氧化物歧化酶（ＳＯＤ）活性的降低；还能明显延长小鼠断头后张口呼吸持续时间。
Puerariae isoflavone (500, 1000 mg/kg×7d, po) significantly antagonized the increase of water、 Ca 2+ and MDA contents and the attenuation of Ca 2+ ATP ase and SOD activity in the brain of rats treated with repeated brief ischemia referfusion, and markedly prolonged respiratory duration after decapitation in mice.
出处
《中国药科大学学报》
CAS
CSCD
北大核心
1997年第5期310-312,共3页
Journal of China Pharmaceutical University
关键词
葛根总黄酮
脑缺血
钙离子
SOD
保护作用
Puerariae isoflavone
Repeated cerebral ischemia
Ca 2+
Ca 2+ ATP ase
SOD
MDA
