老年男性2型糖尿病患者骨质疏松症相关危险因素分析

Correlate risk factor analysis of osteoporosis in elder male patients with type Ⅱ diabetes mellitus

目的探讨老年男性2型糖尿病（T2DM）患者骨质疏松症（0P）的发生情况及其危险因素。方法用双能X线吸收骨密度仪器测定176例老年男性T2DM患者的L2-4骨密度（BMD），根据BMD将其分为元0P组和并发0P组，根据患者体质量变化将其分为体质量下降组和体质量未降组，同时测定生化指标。结果老年男性T2DM患者OP发生率29．5％，胰岛素水平、尿微量白蛋白、病程、体质量指数、体质量下降是其发生OP的独立危险因素。

Objective To investigate the genesis and risk factor of osteoporosis in elder male patients with type 2 dia- betes mellitus （DM2）. Methods Dual energy X ray absorptimmetry bone density instrument was used to measure the BMD of lumbar spines （L2-4 ） of 176 male patients with type Ⅱ diabetes. According to BMD, DM2 patients were divided into osteoporosis group and without osteoporosis group. According to the change of the body mass, DM2 patients were divided into losing of body mass group and no losing of body mass group. Biochemical indicators were detected at the same time. Results the frequence of osteoporosis in elder male patients with type Ⅱ diabetes was 29.5%. The fasting insuling, urina- ry albumin concentration, course of disease, BMI, losing of body mass were independent risk factors of osteoporosis in type 2 diabetes mellitus. Conclusions Lossing of body mass is risk factor of the elder male patients with type Ⅱ diabetes mellitus.