胃癌肝转移介入治疗疗效分析

The Interventional Therapy for Liver Metastasis from Gastric Cancer

目的通过对胃癌肝转移的化疗和化疗栓塞,评价介入治疗疗效。方法81例胃癌肝转移,行选择性腹腔动脉造影、超选择性胃动脉造影及化疗和化疗栓塞后再行肝动脉造影,观察肝转移瘤血供类型,并进行肝动脉化疗药物灌注和化疗栓塞。结果富血供转移15例(18.52%),有效率86.67%;少血供转移66例(88.48%),有效率48.48%,两组之间差异有显著性(P<0.05)。富血供中位生存期11个月,少血供中位生存期7个月。结论动脉内灌注化疗及化疗栓塞对胃癌肝转移的治疗有效,富血供的胃癌肝转移治疗效果较少血供的胃癌肝转移疗效好。

Objective To evaluate interventional therapeutic effect by chemical treatment and chemoembolization for liver metastasis from gastric cancer. Methods Eighty-one patients with liver metastasis from gastric cancer were undergone selective celiac arteriography, uhraselective gastric arteriography and hepatic arteriography after chemical treatment and chemoembolization. Blood supply types of metastatic tumors of liver were observed and metastatic tumors were pert＇used and embolized through hepatic arteries. Results In these cases, there were 15 hypervascular cases（ 18. 52% ） and the effective power of these cases was 86.67% ;66 hypovaseular cases （88.48% ） and the effective power 48.48%. There was significant difference between both types（P 〈 0.05）. The mesolife span of patients with hypervas- cular metastatic tumor was 11 months while that of patients with hypovascular metastatic tumor was 7 months. The mesolife span of patients with hypervascular metastatic tumor was longer obviously than that of patients with hypovascular metastatic tumor. Conclusion Arterial perfusion and arterial chemoembolization are effective in the treatment of metastatic tumors of liver from gastric cancer. The therapeutic efficacy of hypervascular metastatic tumor is better than that of hypovascular metastatic tumor.