玻璃体内注射曲安奈德治疗Coats病渗出性视网膜脱离

The treatment of intravitreous injection with triameinolone acetonide for Coats'disease with exudative retinal detachment

目的观察玻璃体内注射曲安奈德(TA)治疗Coats病渗出性视网膜脱离的疗效。方法12例(12只眼)经眼底检查、荧光素眼底血管造影(FFA)和B超确定的Coats病引起的视网膜脱离患者接受玻璃体内注射40mg/1ml的TA0.1ml治疗,平均随访10.2个月,对比观察治疗前后患眼视力、眼压、视网膜复位情况。结果12只眼中10只眼视网膜复位,占83.3%,随访3个月2只眼因视网膜未完全复位,再次行玻璃体内注射TA;术后视力均有不同程度提高;2只眼眼压升高发生于用药后1周至2个月,经局部用β受体阻滞剂眼压控制正常;1只眼白内障发展。结论玻璃体内注射TA是治疗Coats病引起的渗出性视网膜脱离的有效手段。

Objective To observe the treatment of intravitreous injection with triameinolone aeetonide for Coats＇ disease with Exudative retinal detachment. Methods Coats＇disease with external exudative retinopathy patients decided by checking the eyeground of 12 cases （12 eyes ）, carrying out fundus fluorescence angiography （ FFA ） and B ultrasound check accept the treatment of injecting 40mg/lml TA0. lml into the vitreous body. Tracing down the treatment result of these patients 10.2 months for each one in average, and compare the eyes before the treatment with those after the treatment in the situations of sight, eye pressure, the restoration of retina. Results The retina of ten out of those twelve ill eyes have restored, which are 83.3%. after tracing down for 3 months, the retina of two ill eyes had not restored completely, so these two eyes accepted the injection of TA into the vitreous body again; after the operation, the sight of those ill eyes enhanced in different margins ; after 1 week to 2 months after the operation, the eye pressure of two eyes goes up. After partial β-receiver retarder control, they became normal; The catarael developed in 1 eye. Conclusion Intmvitreous injection with triameinolone acetonide for Coats＇disease with exudative retinal detachment is one effective method.