福建省2000-2006年细菌性痢疾流行病学分析

Epidemiological Analysis on Bacillary Dysentery in Fujian Province,2000-2006

目的了解福建省细菌性痢疾发病规律,掌握流行趋势,为制定细菌性痢疾的防治对策提供科学依据。方法对2000-2006年福建省发生的细菌性痢疾病例作回顾性分析。结果2000-2006年福建省细菌性痢疾发病率波动在5.40/10万～9.28/万之间,年均发病率为7.16/10万。本病全年均可发生,以夏秋季为高峰;各年龄组均可发病,0～5岁婴幼儿发病率最高,为409.74/10万;在不同职业中,发病顺位由高到低依次为散居儿童、农民、幼托儿童和学生。分离的志贺菌对头孢噻肟、环丙沙星及头孢噻酚高度敏感。临床诊断总符合率为81.82%。结论全省菌痢发病率维持在低发水平,但有些地区发病率仍较高。流行菌型不断变迁,志贺菌耐药日益严重,给菌痢的防治工作带来了一定难度。

Objective To explore the onset rules and epidemic trend of bacillary dysentery in Fujian province, and to provide scientific basis for formulating control strategy. Methods Retrospective analysis on bacillary dysentery occurred in Fujian province from 2000 to 2006 was conducted. Results The incidence of bacillary dysentery fluctuated between 5.40 per 100 000 and 9. 28 per 100 000 from 2000 to 2006, with an annual average incidence of 7. 16 per 100 000. This disease occurred in the whole year and reached peaks during summer and fall . Bacillary dysentery occurred in every age group with the highest morbidity in babies aged 0 -5 years. For different populations, the order of incidence （high to low） was as follows： scattered children, farmers, children in nursery schools and students. Isolated Shigella strains were highly sensitive to cefotaxime, ciprofloxacin and cephalothin. The diagnostic accordance rate was 81.82%. Conclusion The incidence of bacillary dysentery kept in a low level in Fujian province, except for in some areas. The continuous variety of bacterial type and the progressive drug resistance increase the difficulty of prevention and treatment of bacillary dysentery.