摘要
目的:探讨联合检测患者血清中P选择素(P-sel)、层黏连蛋白(LN)、α-L岩藻糖苷酶(AFU)及谷酰转肽酶(γ-GT)对提高原发性肝癌的检出率的意义。方法:用ELISA法检测四组人员的P-sel、LN的含量,用全自动生化分析仪检测AFU、γ-GT的含量。结果:肝癌患者血清中四项指标含量及阳性率明显高于正常对照组(P<0.01)、肝硬化组(P<0.05)或乙肝患者组(P<0.01),联合检测四项指标均为阳性的人群,肝癌患者也明显高于肝硬化患者。结论:联合检测四项指标可提高原发性肝癌的检出率,具有较大的临床意义。
Objective：To study diagnostic value of simutaneous detection of P-sel,LN,AFU and γ-GT in patients with primary heptatic carcinoma.Methods：The P-sel,and the LN were examined by the method of ELISA,AFU,and γ-GT were measured by automatic biochemistry analyzer.Results：Compared with control group and hepatitis B group,contents and positive rates of 4 items index in primary hepatolcellular carcinoma patients have Significantly difference（P〈0.01）.The plasm levels of 4 items were significantly higher than cirrhosis of liver group（P〈0.05）.The sensitivity with P-sel,LN,AFU and γ-GT determination was over 90%.Conclusion：The level of 4 items is valuable in detection of multi-serological index have important clinical significance for diagnosis of primary hepatocellular carcinoma.
出处
《临床医药实践》
2008年第5期338-340,共3页
Proceeding of Clinical Medicine
