老年巨幼细胞性贫血68例临床分析

Analysis of 68 Aged Patients with Megaloblastic Anemia

目的探讨老年人巨幼细胞性贫血的病因、临床特点及治疗效果。方法对68例老年巨幼细胞性贫血患者的发病原因、临床特征及疗效进行回顾分析。结果主要病因是营养摄入不足,临床发病过程缓慢,症状隐匿不典型,表现多样,易误诊误治。叶酸、维生素B12治疗效果及预后良好。结论老年巨幼细胞性贫血有逐年上升趋势,早期诊断与治疗对改善多脏器功能,提高生命质量有重大意义。

Objective To study the etiology, clinical manifestations and therapeutic effects of megaloblastic anemia in aged patients. Methods the etiology, clinical manifestations and therapeutic effects of 68 aged patients with megaloblastic anemia were analyzed retrospectively. Results Malnutrition was the chief cause;the course of this disease was slow;the symptoms were atypi- cal and the manifestation was manifold ;all of these leaded to clinical misdiagnosis and mistreatment. Folic acid and Vitamin Bl2 shows good effects on megaloblastic anemia. Conclusions The incidence of senile mcgaloblastic anemia is inclined to increase every year. Early diagnosis and treatment will improve multi-organ function, and enhance the quality of life.