补中益气丸联合易蒙停治疗大肠癌术后腹泻疗效观察

Clinical Efficacy of Buzhong Yiqi Pill Combined with Imodium in Treating Post-operational Diarrhea in Patients of Colonic Cancer

目的观察补中益气丸联合易蒙停治疗大肠癌术后腹泻的临床疗效。方法80例大肠癌术后腹泻患者随机分为两组,对照组40例用易蒙停(盐酸洛哌丁胺)治疗,试验组40例用补中益气丸联合易蒙停治疗,两组疗程均1周。治疗效果以徐忠法五项10分制评价标准制定排便功能检查表,进行综合分析评价。结果治疗结束后试验组肛门控制力、排便感觉、排便次数改善优于对照组,差异有统计学意义(P<0.01或P<0.05)。治疗结束后试验组总的排便功能较治疗前及对照组改善明显,有统计学意义(P<0.01)。结论补中益气丸联合易蒙停治疗大肠癌术后腹泻疗效优于单用易蒙停治疗者。

Objective To investigate the clinical efficacy of Buzhong Yiqi Pill （BYP） combined with imodi- um in treating post-operational diarrhea in patients undergoing colonic cancer surgery. Methods Eighty patients with diarrhea after colorectal cancer surgery were randomized into two groups equally, the control group were treated with imodium （loperamide hydrochloride） and the treatment group treated by BYP combined with imodium. The therapeutic efficacy was analyzed and evaluated comprehensively depending upon a defecation check table devel- oped from the XU Zhong-fa＇s 5-item 10-integrable system. Results After treatment, the improvements of the anal controlling capacity, the defecatory sensation, the frequency of defecation in the treatment group were significantly better than those in the control group （P 〈0.01 or P 〈0. 05）. The integral function of defecation in the treatment group was obvionsly improved by the end of treatment when compared with before treatment and the control group （P 〈0. 01 ）. Conclusion The clinical efficacy of the BYP combined with imodium in treating post-operational diarrhea after colorectal cancer surgery were better than that of imodium alone.