骨与关节肿瘤及瘤样病变2317例统计分析

A statistical analysis of 2317 cases of tumors and tumor-like lesions of bone and joint

目的统计分析桂林地区骨与关节肿瘤及瘤样病变的发病情况。方法本协作组1987年～2007年先后3次对桂林地区近30家各级医院骨与关节肿瘤及瘤样病变病例进行统计。结果总计2317例,良性骨肿瘤947例(40.87%),骨巨细胞瘤135例(5.83%),原发恶性骨肿瘤470例(20.28%),骨转移瘤484例(20.89%),骨瘤样病变175例(7.55%),关节与滑膜肿瘤及瘤样病变106例(4.57%)。良性骨肿瘤以骨软骨瘤最多见为(551例,58.18%),骨瘤(14.15%)与软骨瘤(13.83%)次之。原发恶性骨肿瘤以骨肉瘤(183例,38.94%)与骨髓瘤(175例,37.23%)多见,软骨肉瘤(6.4%)次之。骨瘤样病变以骨纤维异样增殖症(70例,40%)与骨囊肿(66例,37.71%)多见。多种骨肿瘤患者男性多于女性,好发年龄11～30岁,好发部位与股骨与胫骨。结论桂林地区骨与关节肿瘤及瘤样病变发病统计结果与国内外文献报道结果相似,少数病种相对多与收集范围有关。

Objective To explore and study the tumors and tumor-like lesions of bone and joint occurred in Guilin area. Methods Statistical analysis of tumors and tumor-like lesions of bone and joint was conducted three times by Guilin Cooperative Group of Orthopedics from 1987 to 2007, in more than 30 hospitals. Results There were 947 cases of primary benign tumors （40.87%）, 135 of giant cell tumor of bone （5.83%）, 470 of primary malignant tumors （20.28%）, 484 of metastatic tumors （20.89%）, 175 of tumor like lesions （7.55%） and 106 of joint synovial tumor and tumor like lesions （4.57%）. Among benign bone tumors, osteochondroma was the most common （58.18%）, followed by osteoma （14.15%） and chondroma （13.83%）. Among malignant tumors, osteosarcoma （38.94%） and myeloma （37.23%） were both more common, followed by chondrosarcoma （6.4%）. Among tumor-like lesions, fibrous dysplasia （40%） and bone cyst （37.71%） were the most common. Among all patients, there were more men than women. It also occurred most frequently between 11 and 30 years old, and femur or tibia was the most common site. Conclusions The statistical analysis were similar to those in the domestic and foreign literature. There were a few differences was related to the range of case collection.