功能和分子磁共振成像评价肿瘤治疗效果

Functional and molecular MR imaging in evaluating outcomes of tumor therapy

临床上目前主要基于治疗前后的形态学改变评价肿瘤治疗疗效,用于早期预测和评估肿瘤治疗疗效的能力非常有限。功能和分子磁共振成像(MRI)既能反映肿瘤的某些功能状态和分子生物学的信息,又能提供优质的解剖信号,可以用于早期预测和评价肿瘤的疗效。

The evaluation of outcomes of cancer therapy in clinic are largely based on volumetric and morphological evidences. These evidences, however, are very limited in assessing the early effects of therapy. Functional and molecular MR imaging allows co-registration of functional/molecular-based information with high-resolution anatomical detail within the same imaging modality,which makes it possible for assessing the early effects of tumor therapy.