广州市区早孕妇女梅毒与HIV感染的流行病学调查

Epidemiological investigation of syphilitic and HIV infection in early pregnant women in Guangzhou urban center

目的:调查广州市中心区早期妊娠妇女梅毒和HIV感染情况,对筛查阳性的孕妇进行早期治疗和干预。方法:对妊娠12周以内的早孕妇女进行梅毒血清学检查和HIV抗体初筛检查,对确诊为妊娠梅毒的孕妇,按卫生部疾病控制司2000年颁发的《性病诊断标准与处理原则》中的妊娠梅毒治疗方案给予规范治疗;对HIV感染者,给予适当的行为干预,随访并追踪孕妇的妊娠结局。结果:筛查2177例妊娠12周以内的早孕妇女,其中梅毒感染13例,感染率为5.97‰,HIV感染2例,感染率为0.92‰。结论:在妊娠早期进行梅毒和HIV感染的筛查和干预更有利于控制母婴垂直传播及避免其不良妊娠结局。

Objective： To investigate the incidence of syphilis and HIV infection in early pregnant women in Guangzhou urban center to carry out early treatment and intervention for infective pregnant women. Methods： All pregnant women within 12 weeks were screened by syhilitic test and HIV screening test. The treatment according to “ Diagnostic criteria and principles of management of sexually transmitted disease （2000）” was performed for definite syphilis cases and the proper behavior intervention for the cases with HIV infection. These cases were followed up for the pregnant end - results. Results： 2 177 cases were collected. The syphilis infection rate of early pregnant women was 5. 97‰ （13/2 177） and the HIV infection rate was 0. 92‰ （2/2 177） . Conclusion： The screening and intervention of syphilis and HIV in the early trimester of pregnancy is more favorable to control the vertical transmission of infections and avoid the poor pregnancy outcome.