增视口服液质量标准研究

Quality Standard of Zengshi Oral Liquid

目的：建立增视口服液的质量标准。方法：采用薄层色谱法对枸杞、决明子、五味子进行定性鉴别；采用高效液相色谱法测定大黄酚的含量。结果：增视口服液可用枸杞、决明子、五味子进行定性鉴别；大黄酚进样量在0．083-0．416μg范围内与峰面积积分值呈良好的线性关系（r=0．9999）；平均回收率为98．38％，RSD=1、72％。结论：所建标准可用于增视口服液的质量控制。

OBJECTIVE： To establish the quality standard of 1 of Zengshi oral liquid. METHODS： Thin- layer chromatography（TLC） was employed for the qualitative determination of the Lyciurn barbarurn, Cassia obtusifolia and schisandra chinensis. High performance liquid chromatography （HPLC） was applied for the determination of chrysophanol in Zengshi Oral Liquid. RESULTS： The quality standard of Zengshi oral liquid could be established through qualitative determination of the Lyciurn barbarurn, Cassia obtusifolla and Schisandra chinensis .The linear range of Chrysophanol was 0.083--0.416μg （r = 0.999 9）. The average recovery was 98.38% and the RSD was 1.72%. CONCLUSION： The established standard can be used for the quality control of Zengshi oral liquid.