摘要
目的:建立儿咳宁合剂的质量标准。方法:采用薄层色谱(TLC)法对方中莱菔子、浙贝母进行定性鉴别;采用高效液相色谱法测定制剂中黄芩苷的含量。结果:TLC中可清晰检出莱菔子、浙贝母;黄芩苷进样量在0.319-2.640μg范围内与峰面积积分值呈良好线性关系(r=0.9993);平均回收率为99.56%,RSD=0.83%(n=9)。结论:所建标准可用于儿咳宁合剂的质量控制。
OBJECTIVE: To establish the quality stangard of Erkening misture. METHODS: Raphanus sativus and Fritillaria thunbergii were identifided by TLC, and the content of the Baicalin in Erkening misture was determinated by HPLC. RESULTS: The TLC spots of Raphanus sativus and Fritillaria thunbergii were distinctive. The linear range of Baicalin was 0. 319--2.64μg (r = 0. 999 3) . The average recovery was 99. 5696, and RSD was 0.83% (n = 9) . CONCLUSION: This established standard can be used for the quality control of the Erkening misture.
出处
《中国药房》
CAS
CSCD
北大核心
2008年第24期1887-1888,共2页
China Pharmacy