期刊文献+

大剂量甲基强的松龙治疗急性脊髓炎的临床观察 被引量:3

下载PDF
导出
摘要 目的观察大剂量甲基强的松龙治疗急性脊髓炎的临床疗效。方法48例急性脊髓炎患者随机分为治疗组和对照组,分别用甲基强的松龙和氢化考的松治疗,观察其显效率及脊髓功能恢复情况。结果治疗组显效率为75.15%,显著高于对照组的54.2%;治疗组患者在肌力改善时间、膀胱功能恢复时间及自行下地行走所需时间比对照组均显著缩短。结论大剂量甲基强的松龙治疗急性脊髓炎有较好疗效。
作者 孙伟 冯洪山
出处 《医学信息》 2008年第9期1606-1607,共2页 Journal of Medical Information
  • 相关文献

参考文献3

二级参考文献28

  • 1Bracken MB,Holford TR.Effect of timing of methylprednisol-one or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2[J].J Neurosurg,1993,79(4):500-507.
  • 2Gale K,Kerasidis H,Wrathall JR.Spinal cord contusion in the rat:behavioral analysis of functional neurologic impairment[J].Exp neurol,1985,88(1):123-134.
  • 3Muzio M,Chinnaiyan AM,Kischkel FC,et al.FLICE,a novel FADD-homologous ICE/CED-3-like protease,is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex[J].Cell,1996,85(6):817-827.
  • 4Nagata S.Apoptosis by death receptor[J].Cell,1997,88 (3):355-365.
  • 5Hayashi T,Sakurai M,Abe K,et al.Apoptosis of motor neurons with induction of caspases in the spinal cord after ischemia[J].Stroke,1998,29 (5):1007-1013.
  • 6Crowe M,Bresnahan J,Shuman S,et al.Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys[J].Nature Med,1997,3(1):73-76.
  • 7Li GL,Farooque M,Holtz A,et al.Apoptosis of oligodendrocytes occurs for long distances away from the primary injury after compression trauma to rat spinal cord[J].Acta Neuropathol (Berl),1999,98 (5):473-480.
  • 8Ray SK,Wilford GG,Matzelle DC,et al.Calpeptin and methylprednisolone inhibit apoptosis in rat spinal cord injury[J].Ann N Y Acad Sci,1999,890(1):261-269.
  • 9Taoka Y,Okajima K,Uchiba M,et al.Methylprednisolone reduces spinal cord injury in rats without affecting tumor necrosis factor-alpha production[J].J Neurotrauma,2001,18(5):533-543.
  • 10Yan P,Xu J,Li Q,et al.Glucocorticoid receptor expression in the spinal cord after traumatic injury in adult rats[J].J Neurosci,1999,19(21):9355-9363.

共引文献75

同被引文献43

引证文献3

二级引证文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部