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PKB/Akt与头颈部鳞癌靶向治疗研究进展

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摘要 蛋白激酶B(protein kinase B,PKB)/Akt在调节肿瘤细胞生长、增殖,促进细胞侵袭和转移,促进新生血管生成,以及肿瘤细胞产生化疗、放疗耐受性中起着重要作用,PKB/Akt已成为头颈部鳞癌分子靶向治疗的一个潜在新靶点。本文就PKB/Akt的结构、功能和在头颈部鳞癌靶向治疗中的研究进展作一综述。
作者 石艳 柳志文
出处 《北京口腔医学》 CAS 2008年第4期238-240,共3页 Beijing Journal of Stomatology
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