期刊文献+

几种薄膜材料与血液的界面张力比较

Comparison of Interfacial Tension of Several thin Films With Blood Components
下载PDF
导出
摘要 利用不同方法制备了Ti、ZrN、TiO2、DLC、MPC、TiN以及CNX7种薄膜。利用静滴接触角/界面张力测量仪测量了这7种薄膜与丙三醇、甲酰胺、溴代萘三种液体的固液接触角;根据测得的接触角计算了薄膜的表面自由能,并进一步比较了它们与血液的界面张力。结果表明:MPC和CN0.10薄膜具有较低的固体表面自由能,Ti、ZrN和TiO2薄膜与血液组分界面张力值相对较低。CN0.10薄膜对于纤维蛋白原的吸附较少,与血液组分交互反应也较弱,是潜在的抗凝血材料。 Thin films of seven materials (Ti, ZrN, TiO2, DLC, MPC, TiN and CN0.10) were deposited by different deposition systems. Contact angles of the seven thin films were analyzed using static drop contact angle/interfacial tension tester with glycerol, formamide and α-bromonaphtalene, respectively. According to the contact angles, surface energy of the seven films was calculated. Interfacial tension with blood components of the seven films was also compared with each other. The results show that thin films of MPC and CN0.10 have lower surface energy than others. Lower interracial tension is found in. thin films of Ti, ZrN and TiO2. With less adsorbed fibrinogen and weaker interaction with blood components, CN0.10 could be the potential anti-coagulating material.
出处 《中国表面工程》 EI CAS CSCD 2008年第4期14-17,21,共5页 China Surface Engineering
基金 国家自然科学基金(50475012 50730007)资助项目
关键词 界面张力 血液 接触角 表面自由能 interfacial tension blood contact angle surface energy
  • 相关文献

参考文献14

  • 1Cacciafesta P, Humphris ADL, Jandt KD, et al. An ultraflat titanium surface for biomolecule adsorption studies by atomic force microscopy [C]. Sixth World Biomaterials Congress Transactions, Minneapolis: Society for Biomaterials, USA. 2000,287.
  • 2Courtney JM, Lamba NMK, Sundaram S, et al. Biomaterials for blood-contacting applications [J]. Biomaterials, 1994, 15 (10): 737-744.
  • 3Holland NB, Marchant RE. Individual plasma proteins detected on rough biomaterials by phase imaging AFM [J]. J Biomed Mater Res, 2000, 51: 307-315.
  • 4Kaelble DH, Moacanin J. A surface energy analysis of bioadhesion [J]. Polymer, 1977, 18: 475-482.
  • 5Ruckenstein E, Gourisankar SV. A surface energetic criterion of blood compatibility of foreign surface [J]. J Colloid Interface Sci, 1984, 10 (2):436-451.
  • 6Baszkin A, Lyman DJ. The interaction of plasma proteins with polymers. I. Relationship between polymer surface energy and protein adsorption/ desorption [J]. J Biomed Mater Res, 1980, 14 (4): 393-403.
  • 7DeLangis PA, Yen TF. Electronic antihemocoagulation [J]. Biomater Med Devices Artif Organs, 1986, 14 (3-4): 195-225.
  • 8Kawamaoto N, Moil H, Terano M, et al. Blood compatibility of polypropylene surfaces in relation to the crystalline-amorphous microstructure [J]. J Biomater Sci Polymer Ed, 1997, 8 (11): 859-877.
  • 9张安兄,吕德龙,钟伟,程为庄,杜强国.生物材料的血液相容性[J].上海生物医学工程,2004,25(3):53-58. 被引量:27
  • 10霍丹群,詹东妮,侯长军,张文彬,郑书家,任彦荣,陈柄灿.生物材料的生物相容性综合评价研究[J].生物医学工程学杂志,2006,23(6):1350-1354. 被引量:6

二级参考文献31

  • 1田文华.血液相容性研究的困境[J].国外医学(生物医学工程分册),1993,16(5):280-283. 被引量:1
  • 2杨军,刘景江.弹性体改性高抗冲聚苯乙烯的力学行为Ⅰ.拉伸和动态力学性能[J].高分子材料科学与工程,1995,11(2):71-75. 被引量:12
  • 3Kim YH, Han DK, Park KD, et al. Enhanced blood compatibility of polymers grafted by sulfonated PEO via a negative cilia concept. Biomaterials, 2003, 24:2213 -2223
  • 4Mao C, Zhu AP, Qiu YZ, et al. Introduction of Obutyrylchitosan with a photosensitive hetero-bifunctional crosslinking reagent to silicone rubber film by radiation grafting and its blood compatibility. Colloids and Surfaces B: Biointerfaces , 2003, 30:299-
  • 5Setsuko Y , Yuri S , Ken S , et al. Ion-sensor property and blood compatibility of neutral-carriertype poly (vinyl chloride ) membranes coated by phosphorylcholine polymers. Analytica Chimica Acta, 2002, 463: 31-37
  • 6Morimoto N, Iwasaki Y, Nakabayashi N, et al.Physical properties and blood compatibility of surface-modified segmented polyurethane by semi-interpenetrating polymer networks with a phospholipid polymer. Biomaterials, 2002, 23:4881-4887
  • 7Kim YJ, Kang IK, Huh MW, et al. Surface characterization and in vitro blood compatibility of poly (ethylene terephthalate) immobilized with insulin and/or heparin using plasma glow discharge. Biomaterials, 2000, 21:121-130
  • 8Kicheva YI, Kostov VD, Chichovska M. In vitro and in vivo studies of the effect of the concentration of plasticizer di (2-ethylhexyl) phthalate on the blood complitibility of plasticized poly (vinyl choride) drain tubes. Biomaterials, 1995, 16: 575-579
  • 9Wang XH, Zhang F, Li CR, et al. Improvement of blood compatibility of artificial heart valves via titanium oxide film coated on low temperature isotropic carbon. Surface and Coatings Technology, 2000, 128-129:36-42
  • 10Michael VS, Cynthia HG, Maud BG. What really is blood compatibility. J. Biomater. Sci. Polymer Edn., 2000, 11(11): 1165-1182

共引文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部