重视中药引起的肝损伤

Attaching importance to liver injury caused by Chinese herbal medicine

近年来中药及其制成品所引起不良反应的报道有增多之势，中药所致的肝损伤占临床药物性肝损伤总病例的21．0％～51．4％。究其原因，除了没有遵照中医药辨证施治的基本要求乱用、误用中药外，中药本身的不良反应不可忽视。本文就常见致肝损伤的中药及其成分与致肝损害机制，中药肝损害的临床特点，中药致肝损伤的影响因素以及加强预防措施等作一概述。只有在中医药理论指导下辨证施治、合理用药，才是防止中药及复方制剂引起肝损伤的有效措施。

Objective Report of traditional Chinese medicines＇ adverse effect is on the increase. Liver injuries related to Chinese herbal medicine account for 21.0% -51.4% of total clinical drug induced liver injuries. The probable reasons may include unconformation to the basic Chinese traditional medicine rule of treating diseases with different syndromes, abusing and misusing herbs. The side effects of Chinese herbs themselves should not be ignored. This article comprehended the commonly seen liver injuries caused by Chinese traditional herbs with its ingredients, mechanisms, and clinical characteristics. The medicinal herbs and their preparations should be used rationally under the guidance of the theory of traditional Chinese medicine, differentiation of symptoms and the medical skill should be improved, which are the effective measures for avoiding hepatotoxicity.