原发性高血压患者左室肥厚与胰岛素抵抗关系的研究

The Relationship Between Left Ventricular Hypertrophy in Essensial Hypertensive Patients and Insulin Resistance

目的：探讨胰岛素抵抗（IR）与原发性高血压（EH）患者左室肥厚的关系。方法：EH患者98例，另选择健康对照组33例。根据超声心动图（uCG）测定左心室心肌重量指数（LVMI）和室壁相对厚度（RWT），空腹血糖（FSG），空腹血胰岛素（FSI），并根据HOMA公式计算胰岛素抵抗指数（IRI）：IRI=FSI×FSG／22．5，正常个体平均值为2．1～2．7。结果：胰岛素抵抗是高血压左室肥厚的重要危险因素（p〈0．01）。结论：胰岛素抵抗存在于原发性高血压患者中，并与高血压左室肥厚密切相关。

Objective： To explore the relationship between left ventricular hypertrophy in essensial hypertensive patients and insulin resistance, Methods： 98 essensial hypertensive patients are get orgain damage, and choose 33 healthy people as control group. Left ventricular mass index （LVMI） , Horn eostasism odel essesslment insulin resistance（HOMA- IR） was applied to estimate insulin resistance. Result： RI is a important risk factor in left ventricular hypertrophy of essensial hypertensive patients（P 〈 0.01）. Conclusion： RI lie in essensial hy- pertensive patients and have a intensive correlation with left ventricular hypertrophy.