复方牛胎肝提取物对非酒精性脂肪肝的治疗作用

Clinical study of compound embryonic bovine fiver extract in treatment of nonalcoholic fatty fiver disease

目的观察复方牛胎肝提取物对非酒精性脂肪肝（NAFLD）患者的疗效。方法将我院2005年12月-2007年12月的58例NAFLD患者随机分为两组，对照组单纯生活干预，治疗组在生活干预基础上加复方牛胎肝提取物治疗，疗程均为3个月，比较两组治疗前后的肝功能、血脂及肝纤维化指标的变化。结果治疗后两组肝功能、血脂均有改善，治疗组优于对照组（P〈0．05）。对照组肝纤维指标治疗前后差异无统计学意义（P〉0．05），治疗组肝纤维化指标治疗前后差异有统计学意义（P〈0．05），治疗组明显优于对照组（P〈0．05）。结论复方牛胎肝提取物对NAFLD患者有明显疗效。

Objective To analysis the clinical efficacy of compound embryonic bovine liver extract in treatment of nonalcoholic fatty liver disease（NAFLD）. Method 58 patients with NAFLD were divided into two groups： treatment group and control group. Control group was given intervention of life only, while treatment group was given the same treament plus compound embryonic bovine liver extract.The period of treatment of both groups were 3 months, hepatic function, blood lipid and serum fibrosis index were detected before and after the treatment. Results Hepatic function and blood lipid of both groups were improved.Treatment group was improved more than control group, the difference was statistically significant（ P 〈 0.05）. Liver fibrosis index of treatment group improved after treatment, the difference was statistically significant（ P 〈 0.05）. But liver fibrosis index of control group didn＇t improve after treatment. Conclusions The clinical efficacy of cohapound embryonic bovine liver extract in treatment of NAFLD is significant.