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国产盐酸替罗非班在急性冠脉综合征患者急诊介入治疗中的应用

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摘要 目的探讨国产盐酸替罗非班在急性冠脉综合征(ACS)患者急诊介入治疗中应用的疗效和安全性。方法将88例ACS患者随机分为观察组与对照组,观察组在对照组给予阿司匹林和低分子肝素的基础上加用国产盐酸替罗非班,比较两组的疗效。结果治疗7d和30d两组患者主要终点指标发生率间差别有统计学意义(P<0.01)。两组中主要的不良反应是出血,发生率分别为15.9%和10.0%(P>0.05)。结论国产盐酸替罗非班作为一种高效、高选择的血小板糖蛋白Ⅱb/Ⅲa受体抑制剂,与肝素和阿司匹林联合治疗ACS有效、安全。
出处 《实用心脑肺血管病杂志》 2008年第7期23-24,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
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