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尿路感染大肠埃希菌耐药性分析

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摘要 目的:了解尿路感染大肠埃希菌产超广谱β-内酰胺酶(ESBLs)的耐药性,为临床合理使用抗菌药物提供依据。方法:采用法国生物梅里埃公司ATB细菌鉴定仪对大肠埃希菌进行鉴定,药敏试验用K-B纸片扩散法,根据2005年美国临床和实验室标准研究院(CLSI)标准判读结果。结果:336株大肠埃希菌中检出产ESBLs菌113株,检出率33.63%;产ESBLs菌对碳青酶烯类(美罗培南、亚胺培南)、头胞西丁及β-内酰胺酶抑制剂复合物、阿米卡星耐药性较低在0~13.89%,其余抗菌药物产生较高的耐药性。结论:重视产ESBLs细菌检测,根据药敏试验结果合理用药,碳青酶烯类、头胞西丁及β-内酰胺酶抑制剂复合物、阿米卡星是目前治疗尿路感染有效的抗菌药物。
出处 《交通医学》 2008年第4期436-437,共2页 Medical Journal of Communications
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