溶剂对S-氰戊菊酯微乳剂配方筛选的影响

THE EFFECT OF SOLVENTS ON SCREENING OF ESFENVALERATE MICROEMULSION

通过激光粒度分析仪测定乳液的粒径,研究了溶剂(丙酮、环己酮、甲苯、N,N-二甲基甲酰胺)对S-氰戊菊酯微乳剂配方筛选及其稳定性的影响。结果表明,溶剂-原药体系所需的HLB值与表面活性剂的HLB值相一致时才能获得乳液较小粒径的微乳剂,乳液平均粒径随溶剂的用量的增加而增大,以环己酮和甲苯作溶剂能配制成稳定的微乳剂,以N,N-二甲基甲酰胺作溶剂不能形成微乳剂。

The effect of solvents （ acetone, cyclohexanone, toluene and N, N - dimethylformamide） on the screening and stability of esfenvalerate microemulsion was studied by means of diameter mensuration. The result shows that the HLB of the system of solvent - pesticide must be in accordance with the surfactant when getting microemulsion with smaller emulsion diameter; the average diameter of emulsion increases with the increase of solvent. The stable microemulsion can be made with the solvents of cyclohexanone and toluene, but the microemulsion can not be prepared with the solvent of N,N - dimethylformamide.