长期接触低剂量有机磷农药对人体健康影响的研究进展

Progress of Studies on Human Health Impacts of Long-term Exposure to Organophosphorous Pesticides

有机磷农药(OPs)是我国使用量最大的一类农药之一,广泛使用于水果、蔬菜、烟草、棉花等作物。近年来,由OPs引起的急性中毒事件已逐步减少,而长期低剂量暴露OPs对人体健康的危害逐渐引起了人们的重视。越来越多的研究发现长期低剂量暴露OPs与人体肿瘤的发生,不良生殖结局,神经及神经行为功能的异常有密切关系。

Organophosphorus pesticides （ OPs ） are a major type of pesticides being used on fruit, vegetable, tobacco plant, cotton, and ornamental plant in China. In recent years, the cases of acute posioning due to pesticides abuse have been reduced dramatically. However, the adverse effects in human due to the long-term exposure to low doses of pesticides have been of increasing interest in the literature. More and more studies have shown that long-term low level OPs exposure is closely related with tumor, reproductive failure, neural and neurobehavioral outcomes.