2型糖尿病患者的隐性高血压及其对微量蛋白尿的影响

The recessive hypertension in normotensive type 2 diabetic patients and its effects on the microalbuminuria

目的了解血压正常的2型糖尿病患者的隐性高血压及其对尿微量白蛋白的影响。方法36例血压正常的2型糖尿病患者进行动态血压监测和尿微量白蛋白测定,并对监测结果进行分析,以了解其隐性高血压的特点,并根据有无隐性高血压分为两组,比较其尿微量白蛋白的特点。结果36例血压正常的2型糖尿病患者中11例(30.6%)有隐性高血压。隐性高血压组的血压水平、收缩压和舒张压负荷水平均显著升高,尿白蛋白水平增高(132.1μg/minvs8.5μg/min,P<0.01),尿微量白蛋白阳性率也增高(45.6%vs12.0%,P=0.040)。结论血压正常的2型糖尿病患者中隐性高血压的发生率较高,且隐性高血压者尿微量白蛋白排泄更突出。

Objective To investigate the prevalence of recessive hypertension with ambulatory blood pressure monitoring （ABPM） and evaluate its effects on urinary albumin excretion （UAE） in normotensive type 2 diabetic patients. Methods Thirty-six normotensive patients with type 2 diabetes were involved in the study. They were divided into two groups based on with or without recessive hypertension. Patients underwent UAE rate measurement and 24h ABPM. Results 11 cases of 36 normotensive type 2 diabetic patients （30.6%） demonstrated recessive hypertension. The positive rate of UAE in patients with recessive hypertension was higher than increased that in other patients （45.6% vs 12.0%, P = 0. 040）. Conclusions There was high prevalence of recessive hypertension in normotensive type 2 diabetic. Type 2 diabetic patients with recessive hypertension demonstrates higher positive rate of UAE.