奥曲肽持续静脉输入治疗上消化道出血60例疗效观察

Observation on the curative effect of octreotide continuous intravenous infusion in the treatment of upper digestive tract hemorrhage in 60 cases

目的:探讨奥曲肽持续静脉输入治疗上消化道出血的疗效。方法:将60例上消化道出血患者,随机分为治疗组(38例)和对照组(22例),治疗组为奥曲肽联合奥美拉唑组,对照组为单用奥美拉唑组,观察两组的止血效果。结果:用药3～5天后,治疗组止血有效指标较对照组差异有显著性(P<0.05)。结论:奥曲肽联合奥美拉唑治疗上消化道出血有显著疗效,较单用奥美拉唑有止血速度快、输血量减少、早期再出血发生率低的特点。

Objective：To investigate the curative effect of octreotide continuous intravenous infusion in the treatment of upper digestive tract hemorrhage.Methods：60 patients with upper digestive tract hemorrhage were randomly divided into two groups.38 cases in the treatment group were treated with octreotide combined with omeprazole ,while 22 cases in the control group only with omeprazole,their hemostatic effects were observed.Results：Compared with the control group in 3-5 days after administration,the treatment group had sig- nificant difference in the effective indices of hemostasis （P〈0.05）.Conclusion ：The curative effect of octreotide combined with omeprazole in upper digestive tract hemorrhage is significant.It has the following features such as quick hemostasis,fewer venous transfusion and less occurrence rate of early re-hemorrhage compared with that of omeprazole used alone.